This concept seeks to support the NIMH AIDS Research Centers program, including D-ARCs and ARCs. The Centers aim to capitalize on their coordinated infrastructure to advance high-impact, interdisciplinary HIV/AIDS research, including at the intersection of HIV/AIDS and mental health, that is relevant to the NIMH DAR mission.

The Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative plans to continue supporting the development of innovative and transformative neurotechnology tools and approaches that enable the interrogation of cell- and circuit-specific processes in the central nervous system with greater specificity and higher cellular resolution. This concept supports a broad developmental spectrum, from early-stage, high-risk concepts […]

This concept continues the successful NIMH Biobehavioral Research Awards for Innovative New Scientists (NIMH BRAINS) program that encourages potentially transformative high-risk, high-reward research from exceptional early stage investigators. The NIMH BRAINS program focuses on research priorities and gap areas identified in the NIMH Strategic Plan for Research.

The goal of this concept is to continue supporting an integrated BRAIN® Initiative Cell Atlas Network (BICAN) Coordinating Unit for Biostatistics, Informatics, and Engagement (CUBIE) that will (i) enable the exploration of large-scale brain cell atlas data and knowledge, (ii) inspire research in brain function and disorders, and (iii) ensure research rigor and data reproducibility […]

This is a reissue of the informatics infrastructure program announcement for The Brain Research Through Advancing Innovative Neurotechnologies® (BRAIN) Initiative data ecosystem. This program has established domain-specific archives that serve as primary repositories for scientific data generated across the BRAIN research portfolio, providing long-term maintenance, standardized curation, compliance with NIH data management and sharing policy, […]

The goal of this concept is to reissue and extend the NIMH Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Centers program. The ALACRITY Centers program is intended to support high-impact, practice-based research with near-term potential to significantly advance clinical practice and generate knowledge […]

The goal of this concept is to generate comprehensive evidence to determine whether immunotherapeutic strategies, including broadly neutralizing antibodies (bNAbs) and antibody-derived constructs, can safely and effectively target HIV persistence within the central nervous system (CNS) compartment while mitigating neuroimmune dysfunction and improving mental health outcomes.

This effort aims to stimulate research in a major gap area in pediatric psychopharmacology for psychiatric and neurodevelopmental disorders, by encouraging the development of objective pediatric central nervous system (CNS) measures that can be incorporated into pharmacologic trials.

This is a re-issue of a long-standing R25 program announcement. The overarching goals of this initiative are to: (1) complement and/or enhance the training of a workforce to meet the nation’s biomedical, behavioral, and clinical research needs; (2) help recruit individuals with specific specialty or disciplinary backgrounds to research careers in biomedical, behavioral, and clinical […]

The purpose of the Conte Centers program is to support interdisciplinary teams of researchers engaged in novel, creative, and integrated experimental approaches to address high-risk, high-impact scientific questions in either basic neuroscience research or in translational research that will significantly advance the state of the science in brain and behavioral research and provide the foundation […]