The CHD8 gene is associated with some cases of human autism. A new study shows that mice with mutated CHD8 show defects in brain development and behavioral changes, and may give insight into genetic causes of autism spectrum disorders.

New research suggests gadolinium retention may be more widespread and may be present in many more, or possibly all, patients exposed to gadolinium-based contrast agents, according to new research.

Light makes migraine headaches more painful and induces negative emotions and unpleasant physical sensations, new research confirms. Laboratory studies identify previously unknown connections between nerve cells in the eye and neurons in the brain that regulate physiological, autonomic, endocrine and emotional responses. These findings offer promising path forward for researchers in treatment of migraines.

A new way to label neurons when they become active has now been developed, essentially providing a snapshot of their activity at a moment in time.

Healthy adults carrying the gene APOE4 -- the strongest known genetic risk factor for Alzheimer's disease (AD) -- may struggle to adapt their brain activity to increasing cognitive demands as they get older, according to a study.

New research builds on the pioneering use of machine learning algorithms with brain imaging technology to "mind read."

A technique for inserting a gene into specific cell types in the adult brain can be used to alter the function of brain circuits and change behaviors in an animal model. The method will allow scientists to better understand what roles certain cell types play in the brain's complex circuitry. Researchers hope the approach might […]

The blood-brain barrier protects the brain and central nervous system from harmful chemicals circulating in the blood but also prevents delivery of drugs that could help treat patients with brain cancers and diseases. With recent advances in technology, the blood-brain barrier can now be opened safely, noninvasively and in a targeted manner using ultrasound.

An anti-epileptic drug has been tested for its potential impact on the brain activity of patients with mild Alzheimer's disease. The team documented changes in patients' EEGs that suggest the drug could have a beneficial effect.

By combining electrical monitoring of neural activity with machine learning, a team of neuroscientists has tuned into the brain chatter of rats engaged in helping other rats. The results clarify earlier conflicting findings on the role of specific brain regions, such as the insula, in guiding antisocial and psychopathic behavior, and may shed light on […]

Investigators have been examining the use of deep brain stimulation in the treatment of Parkinson's disease in an attempt to optimize treatment effectiveness.

Insulin in the brain may help regulate the hunger sensation and improve functional connectivity in certain cognitive brain regions (default-mode network, DMN *) as well as in the hippocampus and hypothalamus.

Photodynamic therapy is often used to treat brain tumors because of its specificity — it can target very small regions containing cancerous cells while sparing the normal cells around it from damage. It works by injecting a drug called a photosensitizer into the bloodstream, where it gathers in cells, and then exposing the drug-filled cells […]

New research provides the first evidence that cortical targets could represent a novel therapeutic site for improving motor function in humans paralyzed by spinal cord injury.

A new study showed how a male pheromone in mice enhances sexual behaviors in females -- and how it may enhance a different behavior, aggression, in males -- by identifying distinct neural circuits and neurons that generate a particular behavioral response to specific chemical signals. The findings point to a model for further investigating how […]